Kathleen DiNapoli, Ph.D.

202-970-3014
kdinapoli@fenwick.com
Patent Agent
Intellectual Property

Kathleen
DiNapoli, Ph.D.

Kathleen
DiNapoli, Ph.D.

Kathleen
DiNapoli, Ph.D.

Patent Agent
Intellectual Property

Kat is a patent agent in Fenwick’s intellectual property and life sciences groups, where she works with life sciences and biotechnology clients in the United States and globally. With particularly extensive experience with CAR-T, antibody, and cell-based therapies, Kat counsels clients in a variety of technological fields including genome-editing technology, computational biology and bioinformatics, diagnostic technology, microbiology, neuroscience, immunology, developmental biology, plant biology and genetics, drug delivery systems, small molecules, cancer biology, and drug discovery.

In addition to patent drafting and prosecution, she assists with diligence projects, freedom-to-operate analyses, and patentability searches, leveraging her multidisciplinary background to bring a unique perspective to her practice.

Kat received her Ph.D. in Biochemistry, Cellular and Molecular biology with a concentration on biomathematics, bioinformatics, and computational biology from the Johns Hopkins School of Medicine and the Whiting School of Engineering. Her research centered around computational modeling of disease risk, computational cancer biology, and machine learning, and her thesis focused on modeling the mechanics of human pancreatic cancer—including the role of small molecules as potential treatment options. As an undergraduate, Kat’s research focused on biochemistry and genetics working to develop high yielding and stress resistant crops. Kat’s research has been published in several peer-reviewed journals including Cancer Research and Genome Medicine and she has presented at numerous national and international conferences.

While pursuing her Ph.D., Kat co-founded a biotech startup where she was responsible for aspects of intellectual property licensing negotiation, novelty determination and competitive market analysis, stakeholder engagement, and business plan development.

  • DiNapoli, Kathleen T; Robinson, Douglas N; Iglesias, Pablo A; A mesoscale mechanical model of cellular interactions. Biophysical Journal. Vol.120(22): 4905-4917, 2021. Elsevier.
  • DiNapoli, Kathleen T; Robinson, Douglas N; Iglesias, Pablo A; Tools for computational analysis of moving boundary problems in cellular mechanobiology. WIREs Mechanisms of Disease. Vol.13(4): e1514, 2021. John Wiley & Sons, Inc. Hoboken, USA.
  • Maloney, Gregory S; DiNapoli, Kathleen T; Muday, Gloria K; The anthocyanin reduced tomato mutant demonstrates the role of flavonols in tomato lateral root and root hair development. Plant Physiology. Vol.166(2): 614-631, 2014. American Society of Plant Biologists.
  • Surcel, Alexandra; Schiffhauer, Eric S; Thomas, Dustin G; Zhu, Qingfeng; DiNapoli, Kathleen T; Herbig, Maik; Otto, Oliver; West-Foyle, Hoku; Jacobi, Angela; Kräter, Martin; Plak, Katarzyna; Gluck, Jochen; Jaffee, Elizabeth M; Iglesias, Pablo, A; Anders; Robert A.; Robinson, Dougles N; Targeting Mechanoresponsive Proteins in Pancreatic Cancer: 4-Hydroxyacetophenone Blocks Dissemination and Invasion by Activating MYH14. Cancer Research. 15 September 2019; 79 (18): 4665–4678.
  • Peng, Da; Gleyzer, Rachel; Tai, Wen-Hsin; Kumar, Pavithra; Bian, Qin; Isaacs, Bradley; da Rocha, Edroaldo Lummertz; Cai, Stephanie; DiNapoli, Kathleen; Huang, Franklin W; Cahan, Patrick; Evaluating the transcriptional fidelity of cancer models. Genome Medicine. Vol.13(1): 73, 2021. BioMed Central London.
  • Harkey, Alexandria F; Watkins, Justin M; Olex, Amy L; DiNapoli, Kathleen T; Lewis, Daniel R; Fetrow, Jacquelyn S; Binder, Brad M; Muday, Gloria K; Identification of transcriptional and receptor networks that control root responses to ethylene. Plant Physiology. Vol.176(3): 2095-2118, 2018. American Society of Plant Biologists.

  • DiNapoli, Kathleen T; Robinson, Douglas N; Iglesias, Pablo A; A mesoscale mechanical model of cellular interactions. Biophysical Journal. Vol.120(22): 4905-4917, 2021. Elsevier.
  • DiNapoli, Kathleen T; Robinson, Douglas N; Iglesias, Pablo A; Tools for computational analysis of moving boundary problems in cellular mechanobiology. WIREs Mechanisms of Disease. Vol.13(4): e1514, 2021. John Wiley & Sons, Inc. Hoboken, USA.
  • Maloney, Gregory S; DiNapoli, Kathleen T; Muday, Gloria K; The anthocyanin reduced tomato mutant demonstrates the role of flavonols in tomato lateral root and root hair development. Plant Physiology. Vol.166(2): 614-631, 2014. American Society of Plant Biologists.
  • Surcel, Alexandra; Schiffhauer, Eric S; Thomas, Dustin G; Zhu, Qingfeng; DiNapoli, Kathleen T; Herbig, Maik; Otto, Oliver; West-Foyle, Hoku; Jacobi, Angela; Kräter, Martin; Plak, Katarzyna; Gluck, Jochen; Jaffee, Elizabeth M; Iglesias, Pablo, A; Anders; Robert A.; Robinson, Dougles N; Targeting Mechanoresponsive Proteins in Pancreatic Cancer: 4-Hydroxyacetophenone Blocks Dissemination and Invasion by Activating MYH14. Cancer Research. 15 September 2019; 79 (18): 4665–4678.
  • Peng, Da; Gleyzer, Rachel; Tai, Wen-Hsin; Kumar, Pavithra; Bian, Qin; Isaacs, Bradley; da Rocha, Edroaldo Lummertz; Cai, Stephanie; DiNapoli, Kathleen; Huang, Franklin W; Cahan, Patrick; Evaluating the transcriptional fidelity of cancer models. Genome Medicine. Vol.13(1): 73, 2021. BioMed Central London.
  • Harkey, Alexandria F; Watkins, Justin M; Olex, Amy L; DiNapoli, Kathleen T; Lewis, Daniel R; Fetrow, Jacquelyn S; Binder, Brad M; Muday, Gloria K; Identification of transcriptional and receptor networks that control root responses to ethylene. Plant Physiology. Vol.176(3): 2095-2118, 2018. American Society of Plant Biologists.